• Actinonin synthesis Last decade has provided a number of stu

  2022-11-07

  

  Last decade has provided a number of studies indicating that AhR signaling could play a role both in the development and in progression of multiple cancer types, with potential implications for cancer therapy (for review see (Kolluri et al., 2017; Murray et al., 2014)). Activation of AhR is consider

• DAergic as well as GABAergic and glutamatergic neurons send

  2022-11-07

  

  DAergic, as well as GABAergic and glutamatergic neurons, send projections to target forebrain structures, such as the nucleus accumbens (NAc) and medial prefrontal cortex (mPFC), and support diverse functional roles (Carr and Sesack, 2000a, Carr and Sesack, 2000b, Omelchenko and Sesack, 2009, Taylor

• Apoptosis or programmed cell death is a function of biochemi

  2022-11-07

  

  Apoptosis or programmed cell death is a function of biochemical mechanisms, which are energy-dependent. It is considered to be a vital component of many processes such as normal cell cycle, immune mechanism, atrophy, embryonic development and toxin-induced cell death (Elmore, 2007). In addition, apo

• Whereas more research is needed to identify the precise

  2022-11-07

  

  Whereas more research is needed to identify the precise mechanism by which FIN exerts its antidyskinetic effect, the Semaxanib that it can negatively modulate dopaminergic transmission is also supported by our previous findings. Indeed, we have previously shown that FIN completely reversed the beha

• teva 3026 br Methods br Results br Discussion

  2022-11-07

  

  Methods Results Discussion Acknowledgements This work was supported by the National Institutes of Health [Grant R21 NS081429], a Pilot Grant from the Vanderbilt Conte Center supported by the National Institutes of Health [Grant P50 M096972], and by the Department of Anesthesiology at

• Our previous studies found that some

  2022-11-07

  

  Our previous studies found that some steroid mimetic structures such as stilbene, biphenyl, naphthalene and benzothiophene rings were suitable for lipophilic moieties of 17,20-lyase inhibitors, and several inhibitors obtained using a steroid A, C-ring mimetic approach have already been published. Du

• Several approved and or experimental drugs together with nat

  2022-11-07

  

  Several approved and/or experimental drugs, together with natural compounds, have been reported to induce autophagy in different cancer types [70], [71], [72] (Table 1). In the next paragraphs, we will review more in detail a group of these agents selected in relation to their promising future outco

• This project was funded by the University

  2022-11-07

  

  This project was funded by the University of the Philippines Diliman through the Natural Sciences Research Institute with grant No. CHE-09-2-02. Introduction There is compelling evidence for an anti-inflammatory effect of 12- and 15-lipoxygenases through the generation of lipid mediators involve

• This project was funded by the University

  2022-11-07

  

  This project was funded by the University of the Philippines Diliman through the Natural Sciences Research Institute with grant No. CHE-09-2-02. Introduction There is compelling evidence for an anti-inflammatory effect of 12- and 15-lipoxygenases through the generation of lipid mediators involve

• br In vivo visualization of aromatase

  2022-11-07

  

  In vivo visualization of aromatase with positron emission tomography (PET) Positron emission tomography (PET) utilizes the high PEG Virus Precipitation Kit photons formed during the annihilation of positrons to detect the changes in the amount and localization of injected radiopharmaceuticals in

• Inhibition of autophagy has been shown

  2022-11-05

  

  Inhibition of autophagy has been shown to alleviate neuronal damage after cerebral ischemia, both in cell culture and rodent models (Koike et al., 2008, Li et al., 2015, Wang et al., 2016, Zhang et al., 2014, Zheng et al., 2014). Therefore, blockage of autophagy is a potential target for prevention

• 1-NM-PP1 We also measured macrophage infiltration and CLS

  2022-11-05

  

  We also measured macrophage infiltration and CLS presence in peri-gonadal AT from db/db mice and controls. CLS are morphological features within AT that are accurate indicators of adipocyte death and macrophage infiltration [56]. An earlier study showed that CLS macrophages account for >90% of the t

• br Discussion To our knowledge this is the

  2022-11-05

  

  Discussion To our knowledge, this is the first case report that demonstrates the presence of a novel T1151K ALK mutation in a patient with disease progression after crizotinib and then ceritinib. As early as 2011, Zhang et al. identified T1151K among other resistance mutations to crizotinib in Ba

• MHC class II antigen (45-57) [Homo sapiens] AdipoR and Adipo

  2022-11-05

  

  AdipoR1 and AdipoR2 have been reported to be present in almost all type of tissues and low MHC class II antigen (45-57) [Homo sapiens] levels have been observed in white adipose tissue (Inukai et al., 2005). These receptors have been observed to become deregulated with the onset of obesity, resultin

• Among the enzymes involved in adenosine metabolism

  2022-11-05

  

  Among the enzymes involved in adenosine metabolism, adenosine kinase plays an important role in regulating formation and release of endogenous adenosine in cardiomyocytes as well as vascular endothelial cells Decking et al., 1997, Kowaluk et al., 1998, Smolenski et al., 1994. Inhibition of adenosine

11356 records 63/758 page Previous Next First page 上5页 6162636465 下5页 Last page